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My last analysis pointed to IT/PS/Pest giving more actual damage to gathered mobs without the added threat multiplier (as Unholy). That was, um 3.1-ish? So it may have changed since then, but I tend to doubt it. I get the feeling that DnD has always been intended to be a tanking tool.
I don't understand the logic here, though. DnD and Diseases aren't mutually exclusive. Rather, they boost DnD's damage for all specs (just by a lot in Unholy).
DnD IS intended to be a tanking tool. The question is whether or not it is better AoE to use it instead of BB (or HS, in Blood's case). Because you would only use it in a situation with multiple mobs.
Quick Napkin math:
DnD=62 base damage every second for 10 seconds.
Base AP Coefficient .0475.
So, with 4K AP, that's 252 damage every second for 10 seconds for 3 runes, with NO modifiers factored in (2520 damage overall, for 4788 threat without any -threat talents considered).
Blood Boil
Average base damage= 200
AP Coefficient with a disease=.095
So, with 4K AP and no modifiers, that is 580 damage per. With the 30% boost, that is 754 damage. Using DS means you get 3 BBs instead of a DnD (you DON'T gain a DS, since you convert it to two BBs, you just use the runes in a different spot).
So, a Blood DK would get 2262 damage out of using BBs. That is less than the overall DpS offered by DnD.
Every other talent in the tree boosts both equally, as far as I can tell. I'm also assuming that the 4K AP includes the 10% bonus from a Hunter or yourself.
The question for Blood is twofold.
Can your tank can handle that much threat output?
At what point does using DnD or BB become superior to focusing on HS?
For Frost, the water is much murkier. Since they don't have rotations that are easy to compare, I'm not gonna venture into that...